Absolute Neutrophil Count (ANC)
ANC (/μL) from white blood cell count and segmented neutrophil plus band percentages.
Calculator
How it works
What this tool does
It estimates circulating absolute neutrophils using the standard differential formula. It does not replace the laboratory report or clinical context (e.g., marrow suppression, medications, ethnicity-specific references).
Formula
ANC (/μL) = WBC (×10³/μL) × 1000 × (PMN% + band%) ÷ 100
Equivalent: multiply WBC in “per μL as thousands” by the combined fraction of neutrophilic forms.
References
Differential-based ANC is standard in hematology references and oncology supportive-care guidelines; always use your institution’s definitions for fever and neutropenia.
Dosing & care
Rough teaching cutoffs (not protocol-specific)
- ANC < 500 /μL: often classified as severe neutropenia (febrile neutropenia risk context).
- ANC 500–1499 /μL: below many “normal” adult lower limits; correlate with symptoms and trends.
- ANC ≥ 1500 /μL: within many general adult reference ranges (local labs differ).
Neutropenia & fever (teaching)
- Febrile neutropenia management depends on cancer type, expected nadir, predicted duration, and institutional pathways—not ANC alone.
- Verify differential source (automated vs manual) and whether bands are included; trending counts often matter more than a single screen.
- Follow local protocols for antibiotics, growth factors, and outpatient vs inpatient risk stratification.
Educational tool only—not for diagnosis or treatment decisions.