Amanani okucocwa kwe-creatinine atolikwa njani?

≥90 mL/min ibonisa ukusebenza kwezintso okusesiqhelweni (I-CKD ibakala 1), 60-89 mL/min ibonisa ukwehla okuncinci ekusebenzeni kwezintso (I-CKD ibakala 2), 30-59 mL/min ibonisa ukwehla okuphakathi ekusebenzeni kwezintso (I-CKD ibakala 3), 15-29 mL/min ibonisa ukwehla okungamandla ekusebenzeni kwezintso (I-CKD ibakala 4), <15 mL/min ibonisa ukusilela kwezintso (I-CKD ibakala 5).

Isibali Sokucocwa Kwe Creatinine

Iminyaka iminyaka

Isini

Indoda Ibhinqa

Ubunzima kg

I-Creatinine Ye-Serum

μmol/L mg/dL

Ifomula 1: Ccr=[(140-iminyaka)×ubunzima(kg)]/[72×Scr(mg/dl)]

Ifomula 2: Ccr=[(140-iminyaka)×ubunzima(kg)]/[0.818×Scr(umol/L)]

Ukutolika Amaxabiso e-CrCl

Amaxabiso okucocwa kwe-creatinine adla ngokutolika ngolu hlobo:

≥90 mL/min: Ukusebenza kwezintso okusesiqhelweni (I-CKD ibakala 1, ukuba kukho ubungqina bokonakala kwezintso)
60-89 mL/min: Ukwehla okuncinci ekusebenzeni kwezintso (I-CKD ibakala 2)
30-59 mL/min: Ukwehla okuphakathi ekusebenzeni kwezintso (I-CKD ibakala 3)
15-29 mL/min: Ukwehla okungamandla ekusebenzeni kwezintso (I-CKD ibakala 4)
<15 mL/min: Ukusilela kwezintso (I-CKD ibakala 5)

Amaqiniso Nemanani

Ifomula ye-Cockcroft-Gault iqikelela ukucocwa kwe-creatinine njengendlela yokuqikelela ekliniki izinga lokuhluza i-glomerular (GFR). Nangona kunjalo, ukucocwa kwe-creatinine kunokugqithisa ekuqikeleleni i-GFR nge-10-20% kwaye ithathelwe indawo ekusetyenzisweni kwekliniki ziifomula eziqikelela i-GFR ngqo.

Ukongezelela, ifomula ye-Cockcroft-Gault isebenzisa ubunzima, enokungachaneki xa ubunzima buphantsi okanye buphezulu (ubunzima obungaphantsi kunye naxa unobunzima obugqithisileyo). Ukulungelelaniswa nokuqikelela kuyacetyiswa ngokwalandelayo, ngokutsho kukaBrown nabanye noWinter nabanye:

Udidi	I-BMI	Ukubala
Ubunzima obungaphantsi	I-BMI <18.5	Bala usebenzisa ubunzima bokwenene/bonke bomzimba (okutheth' ukuthi, akukho kulungiselela)
Ubunzima obusesiqhelweni	I-BMI 18.5-24.9	Bala usebenzisa ubunzima bomzimba obufaneleyo, ummandla osebenzisa ubunzima bokwenene
Ubunzima obugqithisileyo	I-BMI ≥25	Bala usebenzisa ubunzima bomzimba obulungisiweyo, ummandla osebenzisa ubunzima bomzimba obufaneleyo

Uncwadi

Isalathiso Sokuqala/Esiphambili

Cockcroft DW, Gault MH. Ukuqikelela ukucocwa kwe-creatinine kusuka kwi-serum creatinine. Nephron. 1976;16(1):31-41. PubMed PMID: 1244564.

Imibuzo Ebuzwa Rhoqo

Yintoni ukucocwa kwe-creatinine?

Ukucocwa kwe-creatinine yinkomba ebalulekileyo yokuhlola ukusebenza kwezintso. Iqikelela ukuba izintso zakho zingayihluza kangakanani na i-creatinine egazini.

Ifomula ye-Cockcroft-Gault yahluke njani kwezinye iindlela?

Ifomula ye-Cockcroft-Gault isebenzisa iminyaka, ubunzima, isini, kunye namanqanaba e-serum creatinine ukuqikelela ukucocwa kwe-creatinine, ngelixa ezinye iindlela zinokusebenzisa imigaqo eyahlukileyo.

Kufuneka ndisebenzise nini esi sibali?

Ungasisebenzisa esi sibali xa udinga ukuhlola ukusebenza kwezintso okanye ukujonga iinguqu ekusebenzeni kwezintso.

Ithetha ukuthini imiphumela?

Imiphumela ibonisa izinga lakho lokucocwa kwe-creatinine, ngokuqhelekileyo ngeemililithas ngomzuzu (ml/min). Amanani aphantsi anokubonisa ukwehla ekusebenzeni kwezintso.

Ichanekile kangakanani ifomula ye-Cockcroft-Gault?

Nangona ifomula ye-Cockcroft-Gault isetyenziswa kakhulu, inokungachaneki njengezinye iindlela kwiimeko ezithile, ingakumbi kumaxabiso agqithisileyo obunzima.

Ingaba kufuneka ndisebenzise ubunzima obufanelekileyo, ubunzima bokwenene, okanye ubunzima obulungisiweyo?

Khetha uhlobo olufanelekileyo lobunzima olungqamene ne-BMI yakho. Sebenzisa ubunzima bokwenene xa ubunzima bungaphantsi, ubunzima obufanelekileyo xa ubunzima busesiqhelweni, kunye nobunzima obulungisiweyo xa unobunzima obugqithisileyo.

Ndingasisebenzisa esi sibali kubantwana?

Esi sibali siyilwe ngokubalulekileyo sabantu abadala; ukuhlola ukucocwa kwe-creatinine kubantwana kunokufuna iindlela ezahlukileyo.

Imbeko

Esi sibali sinikwa ngenjongo zokufunda nokunika ulwazi kuphela. Asiyiyo indawo yokutshintsha icebo lonyango lwezempilo lweprofeshinali, uhlolo, okanye unyango. Soloko ucela icebo logqirha wakho okanye omnye umntu oqeqeshiweyo kwezempilo nangeyiphi na imibuzo onayo malunga nemeko yezempilo.

Imiphumela evela kwesi sibali kufuneka itolikiwe ngabasebenzi bezempilo ngokwemeko yesigulana iyonke. Izigqibo malunga nokunakekelwa kwesigulana akufuneki zisekelwe kwimiphumela yesi sibali kuphela.